Coming from the North. Take the A26 motorway (direction Voltri Genova), take the Alessandria Sud exit and follow the signs to Acqui Terme and then for Sassello.
Coming from La Spezia. Take the A12 motorway (direction Ventimiglia), exit at Albisola and then follow the signs to Sassello.
Coming from Ventimiglia. Driving along the A10 motorway (direction Genova), exit at Albisola and then follow the signs to Sassello.